Marya China Supplier Pharmaceutical Injection Vial Glass Bottle Liquid Filling Sealing Machine

Marya China supplier pharmaceutical injection vial glass bottle liquid filling sealing machine 

Main Composition
 

The vial liquid filling line is composed of ultrasonic bottle washing machine, dryer sterilizer, vial filling stoppering machine, and vial capping machine. It can complete spraying water, ultrasonic cleaning, flushing of inner and outer wall of bottle, preheating, drying and sterilization, heat source removing, cooling, bottle unscrambling, (nitrogen pre-filling), filling, (nitrogen post-filling), stopper unscrambling, stopper pressing, cap unscrambling, capping and other complex functions, realizing automatic production of the whole process. Each machine can be used separately, or in linkage line . The whole line is mainly used for filling of vial liquid injections and freeze-dried powder injections in pharmaceutical factories, it can also be applied to production of antibiotics, bio-pharmaceuticals, chemical pharmaceuticals, blood products etc.

Performance Features

1.The aseptic vial filling  line meets new GMP   requirements, and the cleaning effect   meets the new   Pharmacopoeia   standards and requirements.
2.The whole injectable vial filling line can adopt straight-line layout or wall-to-wall L-shaped layout to reduce risk of cross-contamination and ensure aseptic level.

4.Stable product performance, easy and reliable operation, beautiful appearance;
5.High degree of automation, few operators required;
6.Single row or double row filling;
7.Optional real-time display and printing system of sterilization temperature;
8.The heat in the hot air circulation tunnel oven is evenly distributed, and the heat resources removal effect is good.
9.Optional online sterilization function for the cooling section of hot air circulation tunnel oven.
10.Optional open-RABS isolation protection system and class 100 laminar flow hood protection;

11.Optional high-performance no-bottle-no-filling, no bottle no stoppering, no bottle no capping and squeeze stop functions;
12.The capping machine can be equipped with dust exhaust device, which can absorb aluminum scraps produced during capping and thus reduce the risk of environmental pollution.
13.The whole line can be equipped with online monitoring system to monitor key factors that affect product quality (such as dust particles, planktonic bacteria, wind speed, wind pressure, etc.).
14.Full-line linkage control function;
15.To realize fully automatic control and monitor of production process, high precision colored touch screen operation monitoring, PLC automatic control and automatic protection, main machine frequency conversion speed regulation and other control technology are used.
16.Applicable for wide range of bottle specifications, and easy to replace mould.
17.The products can be customized according to customer ' s actual demand.

Technical Parameter

Production procedures:
1.The compact line realizes single linkage, continuous operation from washing, sterilizing& drying,filling& stoppering, and capping. The whole production process realizes cleaning operation; protects products from contamination, meets the GMP production standard.
2.The whole line adopts PLC total control, frequency converter, touch screen control technology, stable and reliable operation.
3.Each machine has a power-off restart data saving function
4.Ultrasonic washing CIP station for the mesh belt of sterilizer
5.No vial no filling, no vial no stopper supply, no vial no capping
6.Automatically reject for the unqualified vials
7.Machine adopts superior SS 316L for part in product contact with product/drugs design to ensure cleaning and no dead angles 
8.Industrial PC control with state of art features for Audit trail, data integrity, Graphical debugging and remote access

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